Mechanical loading, and the associated mechanical stress, shows immense skeletal site-related variation [1], [2].
Mechanical loading influences skeletal structural integrity and bone remodeling.
Mechanical loading plays an essential role in maintaining bone integrity.
Mechanical loading alone did not cause Smad1/5/8 activation.
Mechanical loading is one of the most important physical stimuli for osteoblast differentiation.
Mechanical loading of bones activates modeling and suppresses remodeling by promoting bone formation [ 9].
Mechanical loading mediates endogenous CNP release leading to increased natriuretic peptide signalling.
Mechanical loading promoted increased metaphyseal bone mass in young mice but not in adult mice.
Mechanical loading could reverse the catabolic process induced by the fragments and enhance anabolic activities.
Mechanical loading of the thorax due to adiposity could exacerbate lung volume restriction.
Mechanical loading of long duration may result in strain on the cell.
