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All along a startup's journey, from the initial idea to the growth of a venture into a mature business, challenges arise.
Alan McCrae, head of energy tax at PwC, said: "The UK government has been listening carefully to the concerns of the oil and gas industry and gaining a clearer understanding of the many issues it faces as it seeks to maximise opportunities in a maturing and challenging environment.
The end of protest is the proliferation of ineffective protests that are more like a ritualized performance of children than a mature, revolutionary challenge to the status quo.
The Bessie Barriscale Feature Company released eight films in 1918 and from reviews, it is clear that she abandoned the ingenue role with which she had been associated at Triangle in favor of more varied, mature, and challenging parts.
As the field of therapeutic proteins continues to mature, the challenge of follow-on biologics needs to be addressed with the establishment of regulatory guidelines appropriate for the complexity of biotherapeutics.
While much of gas-liquid separation is considered a mature technology, key challenges remain in designing compact systems – particularly for subsea applications – and heavy oil service.
There are already some large-scale experiments under way but MECs are far from being a mature technology; important challenges, mostly techno-economic in nature (cost of materials, hydrogen management, etc).
This effort presents the characterization of range and position error measurement results which serve as a foundation upon which this system can be matured and remaining challenges can be addressed.
In fact, Global Giving comes from a class of wired social ventures that includes Kiva, DonorsChoose, Change.org, DoSomething and Razoo - all of whom took years to mature and overcame challenges and change along the path.
Our study has also illustrated how the needs of partners change as partnerships mature and new challenges emerge.
The observation that disambiguation is accomplished primarily by mature granule cells challenges the hypothesis that adult-born cells retire from the active population upon maturation (Aimone et al., 2010; Alme et al., 2010).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com