Sentence examples for Marked predisposition from inspiring English sources
The 4,100-employee 4,100-employeehe three companyr scienthats have builtheas mainthreed a marked predisposition toward building and not buying its future.
These clinical presentations, which are secondary to sensitivity to ionizing radiation and a marked predisposition to cancer, were explicated in 1995 by Savitsky et al. as an autosomal recessive mutation in the Ataxia Telangiectasia Mutated (ATM) gene.
However, what exactly causes the marked predisposition for tissue deposition and rapid clearance from the circulation is unclear.
Fanconi anemia (FA) is a recessive disorder associated with progressive pancytopenia, multiple developmental defects, and marked predisposition to malignancies.
Werner Syndrome (WS) is an autosomal recessive segmental aging disorder associated with a marked predisposition to cancer and vascular disease [ 1, 2].
FA is associated with progressive pancytopenia, developmental defects, and marked predisposition to malignancies, especially acute myeloid leukemia and squamous cell carcinoma of the head and neck [ 1, 2].
Loss of WRN causes the progeroid disorder Werner syndrome which is marked by cancer predisposition.
It has been proposed that this mark also confers a predisposition to aberrant DNA promoter hypermethylation of tumor suppressor genes (TSGs) in cancer.
The Diagnosis: Multiple endocrine neoplasia, or MEN, is marked by a rare inherited predisposition to develop tumors, or neoplasia, in various endocrine glands.
Until now, 6 Kabuki patients have been described that developed different types of cancer including pre-B-ALL, hepatoblastoma, neuroblastoma,, Burkitt lymphoma, and fibromyxoid sarcoma marking the Kabuki syndrome as a cancer predisposition syndrome.
It is plausible that a predisposition toward NAFLD could reflect the presence of particularly marked IR and that the development and progression of the liver disease per se (with increasing inflammation and fibrosis) could further worsen IR and thereby increase CVD risk.
