Sentence examples for Marked and widespread from inspiring English sources
This consisted of four categories: Grade 1, tumours showed invasive, well-delineated borders; Grade 2, infiltrating, solid cords, bands and strands; Grade 3, small groups or cords of infiltrating cells (n>15); Grade 4, marked and widespread cellular dissociation in a small group of cells (n<15) and/or in single cells.
With Cd-MEC co-culture, SCs showed a marked and widespread increase in VIM protein, a mesenchymal cell marker, and increased VIM transcript.
Strikingly, marked and widespread signs of dysplasia, with nuclear pleomorphisms and initial loss of normal architecture, heralding malignant transformation, were scored in all the mutant mice exposed to ethanol, but not in the control-fed littermates nor in ethanol-fed normal mice.
EEG evidenced marked and widespread slow bioelectric abnormalities.
Similarly, the Ktrans maps from patient 26 indicate marked and widespread reduction in perfusion of an ovarian carcinoma metastasis at 6 days following CYT997 administration.
In our study, the marked and widespread expression of podoplanin in lining layer cells in RA was not restricted to the apical cell surface.
Still, it is marked enough and widespread enough to be worth respecting, and from our own narrow national perspective it is welcome.
4. FIBROMYALGIA -- A little-understood condition that is marked by fatigue and widespread aches in muscles or joints.
The Broken Word by Adam Foulds 63pp, Cape Poetry, £9 The Kenyan Mau Mau uprising was an eight-year revolt against British rule, which paved the way for independence in 1963 but was marked by gruesome and widespread atrocities.
More national temperature records were broken than in any previous decade, according to the WMO report, and this period was also marked by deadly and widespread flooding, droughts, and other extreme weather.
The reboot comes after a rocky few months for Gawker and Valleywag, marked by widespread layoffs and restructuring that a source close to the company described as a bloodbath.
