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We however prefer Plsek's p-charts over the run or Shwehart charts proposed by Lloyd due to the latter's complexity which makes them difficult to program for them to be produced automatically, and because of the limited population size in some of the participating units which would limit the explanatory power of the run or Shwehart charts.
However, it was shown that Pareto-based MOEAs fail to solve many-objective optimization problems (MaOPs) that are defined to be MOPs with more than three objectives [11], mainly due to the fact that the dominance comparison becomes less effective when the number of objectives increases for a limited population size [12].
The aim of the present contribution is to examine conditions where heterogeneity in the emergence and fixation of beneficial mutations enables the adaptive constraints associated with a limited population size to be overcome.
9 Meaningful correlations were difficult to establish due to the limited population size.
The limited population size also hindered stratification based on disease duration.
For example directional selection, in combination with the effects of limited population size [ 36], might alternatively contribute to this result.
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Additional research is needed to determine whether these larger, but still limited population sizes could achieve management goals.
This may result from the limited population sizes, age differences, and some genotypic combinations of the two loci are unfavorable under some specific conditions.
More precise screening can be performed under greenhouse conditions in limited population sizes, in which the number of vectors per plant can be controlled and feeding on all genotypes can be forced.
Our study has important limitations, including a relatively limited population cohort size, of which 11% of women were found to have endometriosis, and possible selection bias arising from the use of telephone directories for defining the population cohort recruited from California.
Subdivided populations with limited effective population size are, however, also affected by genetic drift [ 80].
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