Sentence examples for Leading-edge analysis from inspiring English sources

Common leading-edge genes of several clusters were determined using the leading-edge analysis feature of GSEA (18).

Overlap among pathways was examined by the "Leading edge analysis" feature of GSEA.

After running GSEA, the leading edge analysis feature of the software was used to examine the genes in the leading edge subsets of selected enriched gene sets.

Core genes ranked at the top or bottom of each pathway gene set were sorted using the leading edge analysis method introduced by Subramanian A. Figure 4A provides a reduced overview of the common core genes shared by multiple pathways.

An individual gene or miRNA target may be implicated in the leading edge of multiple pathways, and the numbers of pathways in which the core genes or miRNAs were implicated were determined by the leading edge analysis.

We therefore used the leading edge analysis tool within GSEA to identify related sets, i.e. those in which the significance is driven by an overlapping subset of genes (the "leading edge").

Gene sets with FDR at or below 0.05 were submitted to a leading edge analysis (LEA).

The number of permutations (gene-set type) was set to 1000, and the results were subjected to leading edge analysis.

To mine out the cancer relevant genes, we performed leading edge analysis of gene set enrichment (GSEA) analysis tool [ 21].

Next, the leading edge analysis tool within GSEA [ 37] was used to cluster significant categories for which common genes accounted for the core enrichment signal.

Related gene sets as defined by leading edge analysis are grouped together in column 2 and the range of q values for these gene sets is indicated.