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That large trial, funded by the NIH, is largely responsible for reversing the prevailing attitude about hormone replacement at menopause.
A large trial is under way.
But in a large trial, the drug did not meaningfully improve vision, they said.
Instead, the agency required that Pfizer first conduct a large trial.
Indeed, a large trial of patients with head injuries showed no benefit.
But the results of a second large trial, announced yesterday, showed no effect.
Recently, a team of researchers designed a large trial to figure that out.
The Women's Health Initiative was not the first large trial to report negative results about hormones and heart disease.
When InterMune then did its own large trial of 330 patients, the drug did not improve lung function.
Radiant is focusing on that, and results of its large trial are to be announced in September.
Even if renal denervation does prove effective in a large trial, it appears not to substitute entirely for drugs.
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