The interaction affinity is low, however, and therefore under the conditions of our experiments the constructs lacking any interchain disulfide bonds are largely monomeric, consistent with the previously published NMR data for NEMO44 111.
Although it has a bad guy, the film still lacks a Bond girl to captivate 007, being played for the first time by Daniel Craig.
"Yonder Stands Your Orphan," for all its color and liveliness, lacks a bonding agent to fasten its disparate strands together.
This conjecture was disproved in 1995 by Arduengo's group, who obtained a derivative of dihydroimidazol-2-ylidene, lacking the double bond.
Compounds lacking the double bond were found to be inactive (e.g. 3-phenylpropionaldehyde and 4-phenyl-2-butanone) (Fig. 1; Table 1).
AtPTR1 (Atransportedransportedi-/tripeptideses with low selectivity as well as substrates lacking a peptide bond.
On the other hand, lacking this disulfide bond may confer more flexibility of movement to domain I and domain III which may provide a functional advantage to AFP.
Other secondary amide compounds lacking a hydrogen bond donor were evaluated, and all had weak antituberculosis activity (see Table S3 in the Supporting Information).
Fatty acids are classified as being either saturated (lacking double bonds between their carbon atoms), monounsaturated (with one double bond), or polyunsaturated (containing several double bonds).
These scaffolds are lacking disulfide bonds that make it possible to produce functional scaffolds regardless of the redox potential of the cellular environment, including the reducing environment of the cytoplasm and nucleus.
ZnT3 dimers lacking dityrosine bonds closely resembled the crystal structure of YiiP (Fig. 6A, ZnT3).
