Sentence examples for Lack of substrates from inspiring English sources

The reduction in protein content with 60%% w/v moisture could be due to insufficient water which did not allow good diffusion of solutes and gas, thereby slowing cell metabolism because of a lack of substrates or through too high concentration of inhibitive metabolites in or near the cell (Gervais and Molin, 2003).

In addition, the inhibition of succinate dehydrogenase, by 3-nitropropionic acid or malonate, mimics HD neuropathology in mice [31], indicating that a lack of substrates for the citric acid cycle and the respiratory chain is implicated in the energy deficit in HD brain.

Also, myocardial tissue amino acids significantly decrease, indicating myocardial energy depletion due to a lack of substrates generated by autophagy.

In fact, there is also a decrease of primary metabolism in the ripe fruit resulting in a lack of substrates essential for the biosynthesis of phenolic compounds.

Generalized impairment of respiration seems to be a consequence of the lack of substrates for complexes I and II and is associated with reduced oxygen consumption in the PINK1 knockdown and knockout cells (Gandhi et al, 2009).

These cycles are presumably necessary to replace F-box proteins which had been ubiquitinated due to the lack of substrates, or to replace F-box proteins which are no more required during developmental processes (Braus et al. 2010).

Furthermore, the increased protease activity at the end of hydrolysis could be explained by the stagnating microbial cell growth due to a lack of substrate, resulting in the digestion of protein-rich cell debris.

We attribute the initial decrease of bacteria in solution to the lack of substrate (the treatments were prepared in DI water) required to support bacterial growth during the early stages of the experiment.

Combining all 5 beneficial substitutions resulted in the mutant HF5 with a 4.7-fold increase in half-life, with thermal inactivation at 93 °C, and complete lack of substrate inhibition toward the substrate p-nitrophenyl-β-d-glucopyranoside at lower reaction temperatures.

Microbial community structure was strongly influenced by the presence or lack of substrate, while the type of amendment (organic or mineral) had an effect on microbial biomass size and activity.

We interpret the lack of difference in heme-levels at 6 h as a consequence of the decreased absolute levels of cell-free Hb and, thus, a relative lack of substrate bringing free heme levels under the threshold of Hpx scavenging capacity.