Although many observational studies have attempted to estimate the burden of RA, a key limitation is the lack of disease severity measures in datasets [17 20].
The lack of increased severity of illness of a pandemic strain was not fully anticipated in most pandemic influenza planning scenarios, although it was accounted for in the influenza severity index developed by CDC in its Community Mitigation Strategy [1].
Another limitation was the lack of disease severity parameters at baseline in a subset of patients.
Other studies have not usually reported on rates of engagement with IPS so it is difficult to compare data but the failure to engage all participants may reflect an individual's lack of motivation, severity of illness or staff attitudes.
The difficulty of assessing infection in donors and the lack of sepsis severity in some cases could explain the absence of an increase in PCT in donors in our study.
The main limitation is the lack of validated pneumonia severity scoring although several pneumonia severity-related variables were collected.
Despite the lack of specific injury severity data in the NEISS dataset, using hospitalization as a proxy for severity, the vast majority of skateboarding-related injuries in the current study were not severe as they were able to be treated in the ED and not hospitalized (96.9%%).
