The lack of propagation-related tau pathology in the dorsolateral cortex, which is close in proximity to the dorsal infusion coordinate and contains the primary visual cortex (Fig. 5), suggests that the hippocampus is the major mediator of tau spread in this model.
Lack of unidirectional propagation due to spurious impurity-driven back scattering is also a concern in integrated waveguides.
The lack of tau propagation to the LGN, a nucleus not connected but in close proximity to the hippocampus, discounts the possibility of tau seeds simply diffusing from the infusion site to distal nuclei.
But, I cannot support the lack of transparency and propagation of misinformation at the management level at this company.
We found that there are a disproportionate number of edges with influence probabilities higher than 0.99, which is due to the lack of sufficient samplings of propagation events over these edges.
The lack of success of vegetative propagation methods mentioned earlier (macroproliferation, 'rhizome'- or 'offset'-based propagation and layering-based propagation) other than cuttings is notorious.
Fungal prions have helped to suggest mechanisms of conversion that may apply to all prions, though fungal prions appear distinct from infectious mammalian prions in the lack of cofactor required for propagation.
This lack of standardization undermines the propagation of knowledge across resources, as well as the credibility of results from high-throughput analyses.
It has been suggested that, due to an apparent lack of microbiological transmissibility and propagation within communities, all amyloidogenic proteins capable of permissive templating be termed "prionoids" [ 27].
