Sentence examples for Lack of junction from inspiring English sources

One of the major causes of such events is lack of junction reads between the cassette exon and constitutive exons, which makes the inclusive isoform not detectable by Cufflinks and Scripture, but still quantifiable by MISO since reads are covering the cassette exon.

Disgruntled drivers also complain about a lack of junctions, while observers speculate about an apparent absence of stations and pedestrian crossings.

Six of those (i.e., R23T, D47N, P88S, P88Q, Gja8-R205G, and E201K) have been found to be mislocalized in the cytoplasm, ER, ER-Golgi intermediate compartment (ERGIC), and/or Golgi apparatus leading to a lack of gap junction plaque formation with a consequential lack of hemichannel currents, gap junctional conductance, and/or dye transfer activities.

Claudin-3 is an important sealing protein and its loss from colon tissue has been correlated with lack of tight junction integrity [11].

A lack of gap junction intercellular communication is common in cancer, and is thought to enable escape of homeostatic control.

Altogether 8 mutations are reported to cause complete lack of gap junction channel conductance (i.e., R23T, V44E, W45S, D47N, E48K, P88S/Q, and Gja8-R205G) (Table 1).

Mutation of the putative v-Src phosphorylation site results in lack of gap junction closure by v-Src in Xenopus oocytes [ 104].

It was observed that the main characteristics of false positive fusions in the negative_set are both the lack of fusion junction-spanning reads and the inclusion of intronic regions in the fusion.

Thirdly, even in circumventricular organs characterized by a lack of tight junctions between endothelial cells, these molecules seem to be unable to enter in sufficiently high concentrations to cause tissue damage in the absence of inflammation [ 5].

Our previous studies have shown greater drug penetration and efficacy in MCC derived from colon carcinoma cell lines with a defect in alpha-E-catenin and lack of adherens junctions [ 3].

Spontaneous activity in sensory axons could be expected to produce a different pattern of changes due to the lack of a neuromuscular junction.