Sentence examples for Lack of goblet from inspiring English sources

However, none of these strategies is completely satisfactory due to lack of goblet cell repopulation, poor mechanical properties or non-standardized preparation procedure.

The lack of goblet cells during allergen challenge to Sox2Δ/Δ mice supports the concept that Clara cell differentiation, dependent upon Sox2, is required for the differentiation of Clara cells into goblet cells following allergen exposure.

Moreover, the individual cells had distinctive elongated and stratified nuclei, loss of polarity, increase in mitoses, and lack of goblet cells (Fig.  1-2).

Based on the phenotypical features of DCs, including the intimate association with lymphoid tissue, the presence of intraepithelial B-lymphocytes and the lack of goblet cells, DC has been suggested to derive from M-cells of the gut-associated lymphoid tissue [ 1].

Similar Agr2 expression levels were observed in wt and Hoxa5 −/− lungs up to day 42 after naphthalene injection, consistent with the lack of detectable goblet cells at this time point and suggesting that abnormal Clara cell differentiation precedes goblet cell metaplasia (Fig. 5O).

p16+ cells generally also lacked markers of goblet cells (mucin vacules and mucicarmine staining) (Fig. 2c e, Fig. S7a d, Supporting information).

This observation corroborates with the findings of Van der Sluis et al whereby the expression of Tff3 was observed, despite the lack of PAS-positive goblet cells.

Mice lacking ITF/TFF3 similarly made normal levels of goblet cell and Paneth cell responses.

It is possible that the lack of staining seen in some goblet cells may reflect the fact that the protein has been secreted into the airway lumen.

Spdef null mice lack conjunctival goblet cells and provide a model of dry eye.

The low-grade areas were well-differentiated, as indicated by the presence of goblet cells, but proliferative as indicated by the high levels of phospho-histone H3 staining and the complete lack of staining for SA-β-galactosidase (Fig 5D).