Sentence examples for Lack of function from inspiring English sources

The lack of effect on telomere length in either TANK1−/− or TANK2−/− single knockout mice could also reflect functional redundancy rather than lack of function of these two molecules.

Midprice Portables Because of the expense of built-in systems and the lack of function of the smaller handheld units, midprice portable models are becoming popular.

Any mutation that results in a lack of function for a particular gene is called a "null" mutation.

This is evidenced by an assortment of dresses, several of them by the imaginative Dutch designer Iris van Herpen, that border on sculpture in their form and lack of function.

This could explain the lack of function common to many schizophrenics and the failure of those hearing voices to tag inner speech as coming from the self.

The shrilling of daytime TV only emphasises the lack of function of people whose wisdom – often forged in adversity and hardship – is of no use to succeeding generations, since they have been born in a later, wiser age, in which such knowledge is, like its possessors, redundant.

While menin is required for Hsp70 expression, the results of epistatic studies indicate that the increase in genome instability observed in Mnn1 lack-of-function mutants cannot be accounted for by mis-expression of Hsp70.

Whether or not the lack-of-function phenotype of Mnn1 mutants can be accounted for by the disruption of the activity of Trx and TAC1 complex remains to be investigated.

This is perhaps not surprising considering that our repeated conditions of heat shock were limited to 20 min and that HSP70 expression was normal for the first 15 min of these treatments in Mnn1 lack-of-function mutants (Fig. 2A).

Therefore, our study investigated a potential endogenous role of prion protein in synaptic signaling, the lack of which could resemble a lack-of-function phenotype in prion disease.

Thus, our data present essential new information possibly related to prion pathogenesis in which a functional synaptic role of PrPC is compromised due to its advanced conversion into PrPSC thereby creating a lack-of-function scenario.