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These observations might explain the lack of emergence of A(H1N1 pdm09 reassortants among swine.
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Author, 'The Law of Emergence'.
Furthermore, lack of efficacy and emergence of side effects may also have led treating physicians to abandon the strategy of polypharmacy.
Second, the purpose of this study is to report conditions of failure due to lack of response or emergence of undesired events, including adverse events, and possible situations of habituation to or dependence on alprazolam.
Many factors have been implicated in treatment failure, including ineffective penetration of antibiotics into the gastric mucosa, antibiotic inactivation by low gastric pH, lack of compliance, and emergence of acquired antibiotic resistance by H. pylori [ 3, 14].
A significant proportion of patients fail to maintain an undetectable plasma viral load (<50 copies/mL) because of a lack of adherence and/or the emergence of drug resistance1,2.
Excessive Na+ also create problems in crop water uptake, poor seedling emergence, lack of aeration, plant and root diseases, etc. (Ayers and Westcot 1985).
Systemic treatments for most solid tumours are limited by lack of specificity and the emergence of drug resistance.
Other related problems such as soil crusting, poor seedling emergence, lack of aeration, plant and root diseases, weed and mosquito control problems caused by the low rate of infiltration may further complicate crop management.
Lack of effective vaccines and emergence of drug-resistant parasites and insecticide-resistant mosquito vectors are the main reasons for the failure in controlling the parasites and the associated disease.
The life on Mars remains an open question because of the lack of proof of its past emergence and its current presence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com