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In this context, homologous genes that differ in expression characteristics despite the absence of any meaningful differences in upstream regulatory sequence architecture should justify examination of the contribution of differential upstream DNA methylation in the expression of the desired phenotype (Figure 3B).
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That would certainly justify further examination".
However, their significant findings justify further examination regarding the benefits of volar locking plates.
Even if the court's approach to statutory interpretation was changing, Justice Breyer wrote, "we could not agree that the existence of such a change would justify re-examination of well-established prior law".
Although environmental restrictions and high operating costs have limited the success of the supersonic civil transport, the appeal of reduced traveling time justifies the examination of a second generation of supersonic aircraft.
The findings of this work, which show a more complex picture of STP radiochemistry than previously considered, coupled with errors in IARC Monograph 89, may justify re-examination of the radionuclides currently identified on the FDA HPHC list.
Consequently, tumour events regulated by CXCL12 seem more complex than previously thought, justifying the examination of earlier findings related to this chemokine in light of an additional receptor.
Owing to a general paucity of data, however, the relationship between blood pressure and other cancer sites is inconclusive and justifies further examination.
The daily clinical experiences in monitoring BC patients after primary therapy demonstrate that any significant increase in tumor markers, even in the absence of other clinical or instrumental signs of cancer, justifies PETCT examination [ 14, 15].
A significant interaction between TP53 status and lymph node categories was seen in Cox regression models (P = 0.0095) and justified the examination of the effect of TP53 status in the nodal categories N1 versus N2 separately.
There is now a wealth of preclinical data which supports a clear scientific rationale for BM-derived cell therapy in MS. This, together with the extensive clinical experience of BM transplantation which has been acquired over several decades, justifies the examination of the putative clinical benefit of BM-derived cell therapy for MS in clinical trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com