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The large heterogeneity in study designs across the included studies precluded formal calculation of summary diagnostic accuracy estimates in most instances.
We refrained from calculation of summary scores.
The estimation algorithm follows, along with the calculation complexity summary.
Analyses included calculation of summary statistics and creation of multivariable logistic regression models.
This involved the numerical summation and averaging of ordinal data during the calculation of summary scores.
Finally, Saudi population 'norms' are not available, which limited the calculation of summary composite scores.
Calculations of summary statistics for the observed data were performed in DNaSP v5 (ref. 66).
A fixed-effect model was used for calculations of summary estimates and their 95% CI.
In that case, power calculations using summary statistics are impractical, whereas exact data simulation is feasible.
With only 16 groups, power calculations using summary statistics would be feasible.
All calculations and summaries were produced using SAS Version 9.2.
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