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While enumerating all possible k-mer (e.g. 256 for 4-mer) is fast, searching through the sequence space to construct a compatible words set is time consuming, especially for TFBSs (PFMs) with relatively long lengths, explaining why MoSta is much slower than KFV (Table S1).
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The result is faster searches with fewer processors.
Namely (i) ESAsearch for fast searching with single PSSMs; (ii) LazyDistrib for exact and efficient p-value computation; and (iii) chaining of single PSSM matches in the form of the chaining method sketched in Section 2.5.
For Google, the hope is that the net effect is not just faster searches, but more searches: "One of the things I've seen in my own personal usage, is that while each search is faster, I spend more time doing searches.
Like blast, a successful structural search system would meet the following specifications: (i) fast, able to search a whole database in interactive time; (ii) accurate in detecting local similarities; and (iii) accurate in aligning amino acids.
The search function is fast and accurate.
"I like SageMaker's fast search and information evaluation tools, that's 60% of why we'd (buy it)," said Putnam, who's in negotiations with SageMaker.
People always mailed us and said how come I can't search my computer as fast as I can search the web?
Is that fast enough?
I searched and I searched.
"I was searching and searching".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com