We take advantage of the parallel presentation in [27] to start the tuning with a parameter set that is already nearly optimized (i.e., the Markov emissions, window size, and other genome-dependent tuning parameters is already close to optimal).
However, Mr Paulson can reasonably argue that this crucial issue is already close to resolution.
A freeport that opened at Changi airport in Singapore in 2010 is already close to full.
If their fears are right, Indonesia may again descend into chaos.It is already close.
Beset by strikes and a failing economy, France is already close to a nervous breakdown.
The labour market is already close to full employment, it's only a matter of time.
The current pace is already close to the 2 percent level the Fed considers ideal for long-term economic growth.
Its benchmark rate of 2.5percentt is already close to a post-World War II low in Europe.
The weaker currency will push up import costs and boost inflation which is already close to the top of the target range of 3%-6 3%-6%
Airports: The options Heathrow third runway One of the world's busiest airports with over 70 million passengers a year, Heathrow is already close to full capacity.
Gina Trapani, founder of the influential blog Lifehacker, said the business card is already close to extinct in places like tech conventions.
