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For example, if Chemical A interacts with Gene B (via a curated chemical-gene interaction), and independently Gene B is associated with Disease C (via a curated gene-disease molecular mechanism or biomarker relationship), then Chemical A is said to have an inferred relationship with Disease C (inferred via Gene B).
For example, if Chemical A interacts with Gene B (via a curated chemical-gene interaction), and Gene B is associated independently with Disease C (via a curated gene-disease relationship), then CTD presents an inferred relationship between Chemical A and Disease C (inferred via Gene B).
When information about the event itself is partially or totally incomplete, a location can be inferred via the organizational sponsorship of the event.
Specifically, although hundreds of regulatory events have been identified or inferred via systems biology approaches, systematic investigation of the functionality of these events in vivo has lagged, thereby preventing the elucidation of regulatory mechanisms and further rational pathway engineering.
A convolutional factor-analysis model is developed, with the number of filters (factors) inferred via the beta process (BP) and hierarchical BP, for single-task and multi-task learning, respectively.
The "universal rule" that results is inferred via a synthesis among the sensible signs that are displayed, and, as a result, among the concepts that the sensible signs illustrate.
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The remaining 80% apparently is mysterious "dark matter"; though it is all around us, its existence is inferred only via its gravitational pull on visible matter.
The periodic classes are inferred exclusively via computational analysis of expression data, and no biological experimental validation has been performed.
The cross-protection effect was therefore inferred indirectly via the analysis of the outputs of the dynamic model for vaccine types 16/18.
Using a computational approach termed 'ACE' (analysis of copy number abnormalities by expression data), Hu et al. [ 58] bypassed direct assessments of cytogenetic abnormalities and inferred them via interrogating clinical microarray expression data of genes according to chromosomal location.
We further inferred their phylogenies via Bayesian inference analysis and predicted gene gain/loss events throughout their diversification.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com