Sentence examples for Inappropriate accumulation from inspiring English sources

Inappropriate accumulation of Kelch, either due to the impaired Cullin3-dependent turnover, or ectopic expression of Kelch, leads to uncontrolled dendritic branching.

Atherosclerosis itself is caused in part by chronic inflammation an inappropriate accumulation in the arterial walls of cells from the immune system.

Mutant APC protein leads to the inappropriate accumulation of ß-catenin transcription co-activator in the nucleus [9], [10].

The lethality of Roc1a mutants is presumably caused by the inappropriate accumulation of at least one target of a Roc1a-containing Cullin dependent E3 ligase [24].

This is illustrated by evidence that inappropriate accumulation of DAG contributes to cellular transformation.

Although cholesterol is an important component of most cells, its inappropriate accumulation leads to obesity, atherosclerosis and diabetes.

2 6–9 Inappropriate neutrophil accumulation within the LP is a key feature of early and active UC.

Results of the present study suggest that inappropriate DAG accumulation in liver cells of hypothyroid animals contributes to PKC depletion.

T-cell resistance against apoptosis contributes to inappropriate T-cell accumulation and the perpetuation of chronic mucosal inflammation in inflammatory bowel diseases (IBDs).

Inappropriate depletion or accumulation of FTH1 may also provide insight into the dynamics of NCOA4 turnover.

Infliximab has been shown to restore the inappropriate T-cell accumulation by induction of apoptosis (Ten Hove et al. 2002).