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In TRANSFORMS, the overall incidence of adverse events was low.
In TRANSFORMS, four other serious infections were reported in patients treated with FTY720, ie, two herpes simplex virus infections and two cases of appendicitis.
A showbiz lunch with a hot potential agent (SNL's Ana Gasteyer, below, who steals every scene she's in) transforms Maria into a lamb; when Maria winds up back in the care of her parents in a flashback, she enters as a little girl.
However, the primary and secondary endpoints were similar to those described in TRANSFORMS.
Two fatal herpetic infections occurred in TRANSFORMS in patients who received fingolimod at a higher-than-approved dose of 1.25 mg: one case each of herpes simplex virus encephalitis and disseminated primary varicella infection.
First, although the efficacy of immunomodulatory therapy appeared to be lower than for FTY720 in TRANSFORMS and parenteral administration is associated with poorer compliance than for oral preparations, the safety profiles of IFN-β and glatiramer acetate are well established by lengthy postmarketing experience.
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If the algebraic functions are valid, their use as plug-in transforms should appropriately linearize the functional forms of the covariates of interest.
"All of us have a stake in transforming the country.
"But then I became interested in transforming the street itself..
Since then, Sirleaf has made impressive strides in transforming Liberia.
Huge technological challenges persist in transforming the energy generation system.
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CEO of Professional Science Editing for Scientists @ prosciediting.com