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In this Investigators' Corner I discuss why such planning is necessary, give an intuitive introduction to the calculations needed to determine required sample sizes, and hint at some of the more technical difficulties inherent in this aspect of study planning.
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In this investigator-initiated study, all researchers were independent of the funding bodies and had complete access to all data.
Mildly depressed type 2 diabetes out-patients were invited to participate in this investigator-initiated 6-month trial.
The clinical areas involved in this investigator driven research are usually those areas of research that have historically been well funded.
In this investigator-initiated pilot study, patients who were scheduled to undergo TACE were randomized to either observation (TACE-O) or intravenous bevacizumab (TACE-BEV).
In this investigator-initiated multicentre randomised long-term maintenance trial, MMF was not significantly superior to AZA in preventing renal flares in patients with proliferative LN, with a renal relapse rate of 19 and 25% in the MMF and AZA group, respectively.
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In agreement with this, investigators from Egypt reported a high proportion (27%) of Manu among their isolates [ 33].
In this case, investigators at the Metropolitan Police's Road Death Investigation Unit come across roughly one incident a year that is similar to Sam Harding's death.
In this mix, investigators believe, tempers somehow flared.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com