Sentence examples for In this checkpoint, from inspiring English sources

These studies showed that SW620 cells undergo synergistic cell death after spindle checkpoint activation followed by cisplatin treatment, suggesting a role of Chk1 in this checkpoint, very likely dependent on BubR1 protein.

Any alteration in this checkpoint causes chromosomal instability, mainly aneuploidy.

In human cancers, dysfunction in this checkpoint is considered a serious pathologic hallmark of neoplastic transformation (Chen et al, 2008).

Defects in this checkpoint are common in many cancers and are associated with aneuploidy generation and tumor progression.

p53, p16 and pRb are key components in this checkpoint, and as such, their inactivation disrupts its normal function.

Proteins involved in this checkpoint pathway are evolutionally conserved among many eukaryotes, including between yeast and humans.

Primary Ctrl fibroblasts displayed a normal G1/S checkpoint arrest, in contrast to A-T fibroblasts in which this checkpoint defect resulted in a significant increase in the percentage of G2 phase cells.

In contrast, in yeast, this checkpoint acts through inhibition of metaphase to anaphase transition.

Bear in mind, this checkpoint is all part of the same security operation, using the same police, that covered the G7.

One of the most prominent border crossing spots for foreign visitors in pre-1989 Berlin, this checkpoint is a grim reminder of the city's progress over the past 27 years".

As there are no sister chromatids in G1, this checkpoint function of cohesin is also cohesion independent.