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In the initial segment I stated that I did not think anyone in that situation should or would be jailed.
b The injected dissected specimen, showing the superficial sural artery (red arrow), which originates from the peroneal artery (pink arrow), accompanied by the lateral sural nerve (yellow arrow) arising from the common peroneal nerve (orange arrow) in the initial segment at the midpoint of the leg (color figure online).
This morphological change was more pronounced in the initial segment, caput, corpus followed by cauda epididymis.
Overall, the expression level of MTA1 protein was higher in the initial segment, caput and proximal corpus than in the other segments.
In contrast to PSD95 and gephyrin, which are localized in the dendrites, ankyrin-G expression is expected to lead to a signal in the initial segment of the ganglion cell's axon, the site of the densest concentration of sodium channels.
At higher magnification, the polymorphic layer of the dentate gyrus contained high levels of GSK3β in both the cell body and in the initial segment of processes (Figure 2B).
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Studies in humans show a preference for routes in which the initial segment had a small angular deviation from the goal vector [1].
Fatt further identified the different regions on the neuron associated with the electrical components of the spike, recognizing for the first time the ways in which the initial segment and soma dendrite determine the action potential properties of central neurons.
Neuronal degeneration as well as other neuropathological features, including abnormal formation of meganeurites (spindle-shaped swelling in the initial segments of axons) and axonal spheroids, and inflammation have been reproduced in murine models of the disease [3], [4], [5], [6].
It is also more common in functional regions and in the initial segments of highly expressed genes.
Hence, we hypothesized that negative TE selection will be stronger in the initial segments of genes to maintain this "ramp".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com