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The specific pattern of [18F]-FDG changes in the foci identified by PET at pre- and post-exposure states are monitored day-by-day.
Furthermore, a higher PRS1 immunoreactivity was detected in the foci corresponding to highly infected cells compared to surrounding uninfected regions (Fig. 4. E, H, I).
From Figure 2, it is clear that annual paths maintained the connections among the sources, which led us to inquire which CTs are responsible for sustaining the repeated infections in the foci CTs.
The IFNβ producers are mostly infected with L. monocytogenes and are exclusively located in the foci of bacterial lesions in the splenic white pulp at the peak of infection.
RPA, PCNA, and DNA polymerase delta are clearly present in replicating foci [ref. [50] and results herein], indicative of the presence of ssDNA at the forks in the foci.
However, a possible explanation for this apparent distal localization paradox may be that MCM-Cdc45 complexes do indeed function directly at forks in the foci, but also simultaneously associate with and provide an unknown function during DNA replication at distal DNA sites (see below).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com