Sentence examples for In tcr from inspiring English sources

In TCR AV gene families, Jα39 and Jα43 showed a predominant usage of 28%; in TCR BV gene families, Jβ2.5 and Jβ2.3 had a high frequency of 37%.

In TCR Vbeta5 transgenic mice, mature CD8+Vbeta5+ T cells transit through a CD8lowVbeta5low deletional intermediate during tolerance induction.

In TCR signaling, two signals of antigen-presenting-cells are necessary to stimulate T-cells.

Consistent with a key role for Rac proteins in TCR mediated signaling, CD4+ T cells from Rac2−/− mice are defective in TCR mediated proliferation and IL-2 and IFN-γ production [45], [46].

The earliest events in TCR signaling must involve the transfer of information from the antigen binding TCR subunit to the CD3 signaling subunits of the TCR/CD3 complex.

Following cloning, 12 TCR clones in TCR AV5S and 8 in TCR BV30 were sequenced (Supplementary Table 3).

Williams, M.S., Noguchi, S., Henkart, P.A. & Osawa, Y. Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death.

Vidal, K., Daniel, C., Hill, M., Littman, D.R. & Allen, P.M. Differential requirements for CD4 in TCR-ligand interactions.

Cytomegalovirus-specific effector function was higher in TCR-transfected TEBV and TM over TN cells.

The impaired host protection in TCR-Vγ4−/− mice correlated well with attenuated recruitment of neutrophils in lungs.

All complexes of T cell receptors (TCRs) bound to peptide-major histocompatibility complex (pMHC) molecules assume a stereotyped binding 'polarity', despite wide variations in TCR-pMHC docking angles.