In such a trial, patients are randomly assigned to either a group that receives an implant or to a second group that does not.
In such a trial, each village would be paired with a similar one not getting the same help—and the results compared.This stirred up a hornets' nest.
In such a trial, clinicians would draw participants' blood, separate out their stem cells and then use a gene-editing tool called CRISPR to fix the sickle cell defect.
In such a trial, patients would be randomly assigned to receive either the actual device or a sham device that looked like it but didn't do anything.
In such a trial, one could treat patients with EM and depression with an antidepressant that did not influence headache (e.g., a selective serotonin reuptake inhibitor or bupropion), predicting that treating depression should prevent CM onset.
In such a trial, the safety of targeting these endpoints must also be evaluated.
In such a trial the assessment of patient outcome should be complemented by the monitoring of ECoG, regional cerebral blood flow, ptiO2 and metabolism.
In such a trial, a large number of patients would be necessary to case-match for their injuries before they are randomized to different treatment modalities.
In such a trial, the power to detect effects of the interventions depends on both the number of schools and the numbers of children per school, and is a complex function of these and the between- and within-school variation in effect sizes.
In such a trial of different caesarean section techniques, using five pairs of possible allocated interventions (1 versus "not 1", 2 versus "not 2", 3 vs. versus "not 3", 4 versus "not 4", 5 versus "not 5"), participants can receive one of 32 possible alternatives.
The University of Wisconsin and the University of California, Los Angeles, are making plans to participate in such a trial, but F.D.A. approval is not guaranteed.
