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However, their use has been limited by a narrow therapeutic range that necessitates frequent monitoring and dose adjustments resulting in substantial risk and inconvenience [1].
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After tendon injury, the scar tissue that replaces the damaged tendon results in a substantial risk for reinjury.
Such type of contamination of groundwater results in a substantial risk to local groundwater resource user and to the environment (Moo-Young et al. 2004).
The law in question in the case defines "aggravated felonies" — which require automatic deportation under federal immigration law — as crimes in which "substantial risk that physical force may be used".
Patients are faced with the responsibility of converting declarative information into procedural application, resulting in a substantial risk of errors [ 4].
The prevalence of A. cantonensis in wild rats and snails in Shenzhen poses substantial risk for future outbreaks of human eosinophilic meningitis.
In view of the substantial risk of hyperkalaemia in CKD patients on RAS blockade in general, this K+ binder is obviously of interest to the nephrologist.
This has increased the total numbers of people at risk of malaria; worryingly, over 50% of the population still live in regions of substantial risk.
Approximately 70% of the electronic waste generated worldwide is processed in China, posing substantial risk to human health and the environment (Ni and Zeng 2009).
Of course, the ICC's prosecutor and judges are themselves taking a substantial risk in the indictment of Bashir.
Frederick: There may still be substantial risk in the market, but additional downside risk equal to that which has already occurred seems unlikely.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com