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nNOS and eNOS may both be involved in sensitisation of peripheral nerves and also central pain pathways.
The TAMH has received support in a series of laboratory investigations that demonstrate short exposure to headache triggers results in sensitisation, whilst prolonged exposure leads to desensitisation [4,5,6,7].
We next used two different strategies for RNA silencing of ftsZ and both resulted in sensitisation of bacteria to berberine, visible as a drop in the Minimum Inhibitory Concentration (MIC).
In contrast, HDAC inhibition has been shown to result in sensitisation to TRAIL-R1 specific apoptosis [ 48, 56].
We have investigated whether this can also be an important mechanism in sensitisation of tumour cells to rhTRAIL.
The notion that exposure to allergens results in sensitisation and that subsequent repeated exposure causes disease is outdated.
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One limitation is the small number of skin prick tested participants, but statistical results demonstrated a significant higher prevalence in SM sensitisation in exposed versus non-exposed workers.
The key finding of reduced levels of specific and total IgE after successful treatment, indicates a reduction in allergic sensitisation in TB patients after treatment for TB.
No large study has described the seasonal variation in asthma attacks in population-based asthmatics in whom sensitisation to allergen has been measured.
In the Netherlands, sensitisation was assessed in a subgroup of children comprising 20% of the original cohort.
Gluatamate, the major excitatory neurotransmitter in CNS plays a key role in the trigeminovascular activation, especially in central sensitisation via activation of NMDA receptors [18, 19].
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CEO of Professional Science Editing for Scientists @ prosciediting.com