Exact(26)
In second line, sorafenib was initially very effective, then, starting from day 84, everolimus effect was more sustained.
In second line, the response rates ranged from 17% (Rougier et al, 1997) to 46% (de Gramont et al, 1997).
In second line, the response rates seem to be lower than those published with oxaliplatin or irinotecan in nonelderly patients.
Pemetrexed and docetaxel are established therapies in second line non-small cell lung cancer (NSCLC).
Because of significant toxicity and limited activity, further investigation of irinotecan plus docetaxel in second line NSCLC is not recommended.
Non-dialyzed patients with SP levels exceeding 5.5 mg/dL were treated in second line with LC [20].
Similar(34)
It is a protease inhibitor, which is useful in second-line treatments for patients who have developed resistance to their first antiretroviral cocktails.
The oral epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitor erlotinib has proven efficacy and tolerability in second-line NSCLC.
Patients treated on arm B, will receive investigator's choice of agents alone indicated for use in second-line and subsequent lines of treatment, but no further bevacizumab treatment.
Because docetaxel has been shown to prolong survival in second-line treatment, a number of novel agents have been combined with docetaxel in order to improve efficacy.
Their role in second-line therapy and beyond, however, has not been systematically examined.
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