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In recruited non-pCR patients, anti-HER2 Th1 repertoire (3.7 vs. 0.5, p = 0.014) and cumulative response (192.3 vs. 33.9 SFC/10, p = 0.014) improved significantly following HER2-pulsed DC1 vaccination.
Except for St. Catherine which had the largest shortfall in recruited participants (11/396; 3%), recruitment was consistent with projections in all parishes (Table 1).
Previous duration of illness was higher in non-recruited patients than in recruited patients, although this finding was not surprising, since a duration of illness of more than seven days was a common reason for exclusion from the study.
Most recently conducted clinical trials evaluating new treatments for macular edema secondary to RVO, included none or only few patients with iRVO based on previous definitions (i.e. few patients with sizeable areas of retinal ischemia were recruited in these trials) and, thus, it is unclear whether the results observed in recruited patients could be extrapolated to those with retinal ischemia.
At PEEP15 EFL patients had a significant better compliance (50 ± 21 vs. 30 ± 12 ml cm H2O, p < 0.05) with no change in recruited lung volume (393 ± 271 vs. 347 ± 203 ml) and tended to be more hypoxemic than NFL patients.
These differences may be associated with differences in recruited patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com