In order to pinpoint the exact Cullin(s) involved in regulation of ZNRF3, we screened a panel of Cullin proteins, and observed that Cullin 1, but not other Cullin proteins, could interact with ZNRF3 (Fig. 1C).
In order to pinpoint a faulty test instrument in a multisite testing system we compare the performance of each test instrument to the overall performance of all the parallel instruments in the system.
In order to pinpoint the role of DNA-PK, we employed synthetic siRNA to target DNA-PKcs mRNA.
In order to pinpoint the alleles that confer an effect on MS susceptibility, a stepwise logistic regression was performed on all the alleles with frequency above 5%.
In order to pinpoint more precisely the area of deletion, nested PCR with pairs of specific primers was designed according to the earlier PAMP results.
In order to pinpoint anastomotic events, a 28 hpf Tg(fli1: EGFP)y1 [10] zebrafish embryo was visualized by fluoresence microscopy until sprouts from adjacent ISVs could be seen to contact one another.
In order to pinpoint the time point at which the phenotype first manifested, earlier developmental stages were analysed.
In order to pinpoint the involved elements we separated the eight module families into TFBS families and individual TFBS (Table 5).
In order to pinpoint the countries and regions where differences between sources are particularly large, future studies adopting a country and regional approach would be of interest.
In order to pinpoint the significant differences between the two profiles, data were analyzed with the software Genomic Workbench 7.0 in combination with the hypergeometric tail algorithm.
In order to pinpoint the value for money of maxillary overdentures based on six instead of four implants more precisely, future research should thus specifically intend to provide more detailed insights into patient satisfaction.
