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In one hypothesis, Fujinaga et al.
In one hypothesis for the pathogenesis of RA, ACPAs bind to these citrullinated auto-antigens in the synovial tissues and form immune complexes that induce inflammatory processes [ 15].
In one hypothesis, miRNA themselves may be the targets of other miRNA and hence the increase of one miRNA may cause a net increase in gene expression because of its repression of another miRNA targeting the same genes.
In one hypothesis, it is suggested that neuronal tissue is hypersensitive to hormonal deficiencies and are more vulnerable to possible subclinical hormonal deficiencies not detectable with routine laboratory tests [ 27].
"Tangible, rational, explicable: that's how you have to think … The danger is that you get stuck in one hypothesis".
Phenotypes that were significantly associated (p<0.0028, alpha = 0.05 corrected for 18 CpG loci; pα=0.05=6.7×10-5, if all 42 MetS phenotypes are treated as non-independent traits in one hypothesis) with the methylation status of at least one site or the regional average are shown in Table 3 and Figure 2.
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Senior party sources are working on one hypothesis in which the Lib Dems might increase their number of MPs from 63 to 80 while the Labour party falls from its current 350 MPs to a possible 160.
Thus, in T1D one hypothesis has linked the augmented secretion of GH with the development of diabetic retinopathy [ 7] and nephropathy [ 8].
Although it is not completely clear how alterations to non-DNA-contacting residues could alter the expression of a gene in trans, one hypothesis is that these fingers may actually facilitate protein protein rather than protein DNA interactions.
The key result reported by Elena and Lenski, based on the standard tests, was that there were many significant epistatic deviations in both directions, in contrast to one hypothesis that predicted negative epistasis should be the general rule [ 17].
By comparing the datasets it was possible to assess that the date palm had various uses in this site: one hypothesis involves its offering in ceremonial practices.
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