Exact(60)
In Mtb BfrB, these residues correspond to E54, E131, E134 and E135, respectively.
In MTB 2, genes encoding CBX5, HMGA2 and RNF20 are annotated by the GO term "heterochromatin".
In Mtb, damage-induced base-substitution mutagenesis is dependent on dnaE2.
Two genes encoding chorismate mutase have been identified in Mtb.
For some molecules there may be many potential targets in Mtb.
Polypharmcology is a preferred strategy to target more than one protein in Mtb.
However, the molecular mechanisms of multiple-magnetosome-chain arrangements in MTB remain largely unknown.
It was shown that combining FolP2 and FolP1 inhibitors can overcome the resistance in Mtb [38].
Therefore Rv3371 is likely involved in Mtb growth arrest and cell wall alterations during persistence.
Transposon mutagenesis studies in Mtb, however, indicate that Fum is required for optimal growth.
Also it would appear this group did not take advantage of known ligands and their targets in Mtb.
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