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"Congenital defects in mismatch repair are known, for example, to cause a hereditary variant of colon cancer".
Countries differ markedly in mismatch patterns (Fig. 3).
He compared those animals with another mouse strain with defects in mismatch repair.
By contrast, not a single one of 25 colorectal patients lacking mutations in mismatch repair genes responded.
A decade ago, scientists linked mutations in mismatch repair genes to a rare cancer called hereditary nonpolyposis colon cancer.
Muir Torre syndrome (MTS) is a rare autosomal dominant genodermatosis caused by mutations in mismatch repair genes.
With no interlayer the difference in mismatch between epilayer and substrate causes a large misfit and thermal strain between them.
Lynch syndrome (LS), or hereditary nonpolyposis colorectal cancer, is caused by mutations in mismatch repair (MMR) genes.
The Hopkins group wondered if patients with many cancer types who had tumors with errors in mismatch repair genes would respond to PD-1 inhibitors.
It is well known that neat carbon materials possess a very high conductivity, resulting in mismatch impedance, thereby inducing very limited microwave absorption [13,14].
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For OrthoCluster we already noticed a strong increase in running times on the simulated data sets, whereby the running time increased dramatically for higher in-mismatch parameters.
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