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However, only in HepG2 cells SREBP1 expression was altered in the presence of SIRT1 siRNA/ORF in concordant to miR-128-2 miR-128-2 miR-128-2
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Alterations in the genomic dosage of the Adh1 gene from 1 to 4 copies do not result in concordant changes to the expression level [ 8].
All five genes showed significant fold-changes in a direction concordant to that as observed in the microarray, confirming the validity of the results (Figure 2).
To further estimate the accuracy of cross species mapping, we used the information from paired reads to determine the percentage of reads that mapped in concordant pairs to the same gene.
The expression pattern of mammaglobin A in malignant and normal samples from different tissues was in general highly concordant to that of lipophilin B (compare e.g. Figure 2A and 2B for breast tissue), except for kidney and prostate samples, where only lipophilin B but not mammaglobin A was expressed.
Data presented in this study are concordant to those obtained in other countries [ 8, 9].
The disparities observed in this study are concordant to what is reported in the literature.
Measurements And Results: Phasic MHI-related increments in mean inspiratory airway pressure were concordant to changes in mean pulmonary artery pressure (MPAP) (r2 = 0.67) with a 0.6 mm Hg rise in MPAP per cm H2O airway pressure.
Using quantitative methylation-specific PCR, Reesink-Peters et al. [41] confirmed that DAPK methylation levels in cervical scraping samples were concordant to the levels in paired tumor tissue specimens.
Although we anticipated similar variant calling issues as observed in the WGS data, interestingly, WES variant calling in CYP2D6 was highly concordant to targeted genotyping and no position exhibited similar rates of missing data.
We also tested whether the CpG island mapping PTTG1 proximal promoter evidenced a differential methylation pattern in differentiated thyroid cancer biopsies concordant to their PTTG1 immunohistochemistry status.
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