Sentence examples for In awd from inspiring English sources

In awd mutant cells p-H3 staining is detectable after stage 6.

In awd mutant cells, the level of Notch-Avl colocalization increased by 2 fold.

In awd mutant follicle cells and wing disc cells, Notch accumulates in enlarged early endosomes, resulting in defective Notch signaling.

In awd + cells, NICD is in small punctates with partial co-localization with Avl, a component of the early endosome, consistent with previous observations [ 34, 55].

In awd + cells, NICD is found in both Rab5CA-positive and -negative vesicles, and, importantly, the detectable NICD is almost exclusively in the lumen of these vesicles.

In awd mutant, on the other hand, accumulated Notch is mostly on cell surface or in Avl-positive early endosomes at 20 minutes and remains in these early endosomes even one hour after internalization.

In addition, the known Notch down-regulation target cut[ 40] is over-expressed in Awd-negative cells.

In contrast, expression of the UAS-NEXT transgene [ 55] in the awd clone (GFP-positive cells in Figure  4C) did not rescue Notch signaling as assessed by loss of GbeSu(H) m8 -lacZ expression (GFP-positive cells in Figure  4D) and loss of Hnt expression (GFP-positive cells in Figure  4E).

Null mutation in the awd gene, the unique NDPK coding gene in Drosophila Melanogaster causes lethality in larvae [10].

In addition, the Notch-containing vesicles in MARCM awd mutant clones are not Rab11-positive recycling endosomes, either (GFP-positive cells in Figure  6D; see Additional file 8: Figure S8 for statistical analysis).

It shined well in the water-slicked apexes in the Tennessee mountains, though at times displayed its heft – especially in the AWD Sport.