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While this segment is good for modeling the structure locally, extension of the alignment to cover the entire domain results in a wrong fold prediction.
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We speculate that the fusion protein TrxA expressed in the pET32a vector could have increased the load of the cells, resulting in the wrong folding of the MCO, which may become an inclusion body.
Diodes conduct in a wrong way.
Some men have used condoms but in a wrong way.
Deregulated apoptosis ultimately leads to increased amounts of apoptotic cells at the wrong time or in a wrong micro-environment.
Chaperones play a key role in the heat shock response, as they are involved in promoting the acquisition of the native conformation by proteins that suffered denaturation and present the wrong folding.
The reason for rereading the two false negative cases in frozen section analysis of the CNB was one mucinous carcinoma, which was found later in deeper paraffin section slides and a wrong orientation with folding the core biopsy specimens, respectively.
Are we wasting time in our search for cytoskeleton-related activities just because the fold triggered a wrong name?
We believe that this is a wrong prediction since in the canonical RNase H fold, β3 is an edge β strand, which can usually be misidentified as an α helix because of its solvent sequence property [ 44].
In fact, they recover a wrong secret.
In both retail and service jobs, there is a right way and a wrong way to do every single thing to fold clothing, wear your uniform, stock products, put milk in a refrigerator, and so on.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com