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Our data presented here suggest that TDP-43 may promote miRNA biogenesis and interact with miRNAs to regulate their function in cancers in a highly complex manner.
It is tough to forecast how this situation will develop as political, economic and technological issues interact in a highly complex manner.
There is a considerable amount of research and documentation related to mean genomic GC content in prokaryotes demonstrating that this property is the result of many factors interacting in a highly complex manner [ 29].
This suggests that Reelin may function as an extracellular modulator of transmembrane receptor signaling, which orchestrates diverse cellular signaling responses depending on different receptor binding affinities, tissue expression patterns and availability of complementary ligands in a highly complex manner.
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Modern concepts regard caries as an interaction between genetic and environmental factors, where biological, social, behavioural and psychological factors are expressed in a highly complex interactive manner with the dental biofilm as the key element [ 1].
Finally, we show how TF concentration can modulate many aspects of the promoter activity in a highly complex and flexible manner, suggesting the transcriptional regulation as a central piece for the cell to control and take advantage of stochasticity.
NO is known to be a mediator of Ca2+ homeostasis in a highly complex and cell-specific manner and although Ca2+ homeostasis has been explored in human oral cancer cells, the exact mechanisms are not completely understood.
Cash's message has clear relevance for global development, a highly complex system in itself.
"That is a highly complex cognitive process".
This is a highly complex conflict".
Counterfeit trade is a highly complex phenomenon.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com