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In addition to identifying disruptions of terminal steps, we also identify complex disruption combinations in upstream pathways that indirectly negate the targeted output by propagating their action through the signaling cascades.
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The framework we've offered above is also useful for identifying disruption opportunities or, if you're an existing intermediary, threats.
As another example, the CMO directly challenged her team to identify disruptions that would deliver on the department's and firm's goals — to bring a more demand-centric perspective to key business challenges.
Over the past several decades, work in neuroscience, psychiatry, psychology, and biology have uncovered key processes underlying, and structures governing, emotional responding and learning, as well as identified disruptions in the structural and functional integrity of these brain regions in models of pathology.
Futures Clinique is a participatory and exploratory futures workshop used to tackle uncertainties, identify disruptions and generate innovations [72].
This paper introduces, illustrates and evaluates the concept of Futures Clinique, which is a participatory and exploratory futures workshop and a collective futures research method to tackle uncertainties, identify disruptions and generate innovations.
This study aimed to identify disruptions in molecular pathways caused by the partial trisomy of mouse chromosome 16 (MMU16) harbored by Ts1Cje mice, which results in neuropathology similar to that observed in people with DS.
Therefore, we used the DGAP105 translocation breakpoints to gain insight into the proband's phenotype and identified disruptions in two genes, MATR3 and AHDC1, which together account for many features of the proband's phenotype.
In light of recent clinical trials for CD47-blocking therapies in cancer treatment, these findings identify disruption of the CD47/SIRPα axis as a potential immunotherapeutic strategy for SCLC.
How can anyone identify disruption to the notoriously fickle climate of the UK? None of the extremes that we are told are now the norm are actually, well, extreme – unless you mean extremely quiet.
Today, few companies identify disruption as a threat.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com