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As expected, the wild type, but not the mutant hnRNP I, was recovered from the RoR RNA precipitates, thus demonstrating that RoR preferably interacts with p-hnRNP I. To determine the minimal region required for p53 repression, we made two additional deletions and narrowed down the active region within a 165 bp fragment (E4-d3B) (Supplementary information, Figure S9A).
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