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SUNDAY'S PUZZLE — The first theme entry I solved in Alex Vratsanos's and Jeff Chen's "Matching Wits" puzzle was the venerable father of modern blues MUDDY WATERS, so as a nod to him, today's blog post will be written in the rhythm of a blues riff.
The AcrIIA6 HTH domain is part of the dimerization interface, which is also similar to that of the bona fide HTH domain present in an E. coli controller protein C.Esp1396I solved in complex with dsDNA (PDB 3s8q 37.
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"I translate their questions and problems that are in apparently unrelated situations, using words and statistical concepts that are more familiar to me, and then try to form links with previous problems I have solved in the past.
Though he kept careful notes about his treatment and joked with Schlesinger of writing up his one-man trial for The New England Journal of Medicine — in a case study titled "My Tumor and How I Solved It" — in the end there wasn't any proof.
"I solved the case in my head," he had said earlier in the day, sitting in a hallway of the New York Public Library, just below the carrel-filled study where he wrote a good portion of the book.
The doctors couldn't solve, but after two weeks on the internet I had them solved and I had them solved in a very simple manner.
I solved the problem in about 20 minutes.
"I solved the maze in fifty-three seconds, but it was a Monday level".
FRIDAY'S PUZZLE — I solved this one in a clockwise pattern, and I suspect that Joe DiPietro needs some cheering up.
The first clue I solved was back in the Precambrian era, so I can't really remember it.
I solved the problem in my house by spraying the bed and enclosing both the mattress and the box spring in separate plastic mattress covers that I could zip up and make airtight.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com