Exact(7)
That, and sitting with it — letting myself actually feel it, not forcing myself to think I should already be "OK" or "moving on".
All these things I felt I should already know — as New Yorkers feel we must — and yet the history of our city is endless, each block a trove of art, architecture, politics, music and literature that no one can ever fully master.
My mental alarm clock is going off, telling me I should already be awake.
At college, I will really have a hard time understanding lectures based on material that I should already know.
When will America GET THE GODDAMNED GUTS to inform me about stuff I should already know about!
"Do you get burned?" "No," she replied, letting it hang in the air as if I should already know why she would want to protect the fairness of her skin.
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From leadpenny at 9 19: It should already be down.
Really it should already be.
But it should already be abundantly clear.
There is a lot of discussion about whether Berlin i) should have already had a few big exits (there have been a few in the several hundred million range; but we are talking $500m+ ,ideally $1bn+) ii) should have some big exits soon (next 1-2 years) or iii) should avoid (premature) exits and focus on growth, as its companies are comparatively young.
Ideally, phase I trials should already include biomarker discovery, with further validation of potential biomarkers in phase II and III trials, including determination of proper cutoff values for biomarkers [ 77].
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