However, CK2-I-mediated sensitization of p53 null cells to TNF α could have resulted from downregulation of NF- κB activity.
Activity-dependent changes in spinal function encompass long-term potentiation (LTP) of individual synapses as well as an increase in neuronal and non-neuronal excitation in the spinal dorsal horn, leading to increased pain sensitivity, i.e. central sensitization (Ji et al., 2003; Sandkühler, 2009).
For control purposes, groups were included which received only prophylactic immunization, but no sensitization (i.e. group P+/S−), neither prophylactic immunization nor sensitization (i.e. group PBS) or only sensitization (i.e. group P−/S+).
On the contrary, it indirectly contributes to the initiation of central sensitization; i.e., sensitization of the spinal cord nerves.
The linear increase, i.e., sensitization of pain scores, was not different between phases.
This disrupted random grain boundary network and large fraction of low CSL boundaries reduced the propensity to sensitization, i.e. carbide precipitation and Cr depletion.
Weekly dosing produced tolerance to nicotine's decreasing effects on vertical activity and increases (i.e., sensitization) in horizontal activity at all doses, and these effects persisted for at least 3 weeks.
The present study was designed to explore in rats whether repeated exposure to ethanol during infancy modifies subjects' sensitivity to the stimulating effect of the drug, either increasing or decreasing its magnitude (i.e. sensitization or tolerance, respectively).
The few studies in which the dynamic behavior of responses was analyzed using successive blocks of a few averagings were unable to find clear evidence for sensitization, i.e. for increased amplitude of the first block.
Five days after FITC sensitization, i.e. after memory T cells were generated, mice ears were challenged with FITC to induce CHS reaction.
