Classification according to protein function encoded by these 31 genes showed that the main regulated cellular processes during this differentiation were (i) remodeling of the extracellular matrix, particularly, sulfated structures, (ii) down-regulation of O-mannosyl glycan biosynthesis, and (iii) an increase in adhesion protein expression.
One explanation is that lipid free apoA-I, generated in vivo through an apoA-I remodeling cycle is rapidly lipidated by ABCA1, or may be incorporated in preexisting plasma HDL [135].
"I remodelled, but I left it so that when danger threatens I can still take refuge in the redoubt".
Therefore, for MHC I, remodeling of MHC II trafficking in antigen-presenting cells or perturbation of the antigen-presenting compartment is of particular interest for CMVs to disrupt the development of the specific immune response.
In addition to MHC I, remodeling of endosomal trafficking during the early phase of MCMV infection can contribute to other immunoevasion activities of MCMV, especially the downmodulation of NKG2D ligands.
We classified these genes into 3 groups, according to the function of the proteins they encode: (i) remodelling of the extracellular matrix where genes are predominantly up-regulated such as Chst5; (ii) glycan biosynthesis with more particularly an up-regulation of genes involved in core 2 glycan synthesis; (iii) adhesion where genes are mainly up-regulated such as Itga11.
"For 13 years I've been here, I've remodeled my building on my own and I've chased criminals and drug dealers," he said.
Or that the bathroom I recently remodeled may have increased my property value by $33,490 (thank you, Zillow.com).
"When the housing market boomed, I bought, remodeled, and flipped properties for a profit".
