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For a set of d concentric circular contours, and taking into account an additive noise due to the presence of noise pixels, a signal component z(i) reads: z ( i ) = ∑ k = 1 d exp ( - j α ( i - 1 ) r 0 k ) exp σ k 2 α 2 ( i - 1 ) 2 2 + n ( i ).
The descriptor is a base 4 representation of the 13-mer generated by the formula
The probability of observing c i reads for k-mer i can be found by marginalizing out z i: (2) where are the mixture proportions.
For a diploid individual (i), a specific biallelic base position is sampled at random N i times (i.e. N i reads) from a large pool of sequences.
The data vector X ∈ ℕ n records the count X i of each haplotype i among N = ∑ i = 1 n X i reads sampled in total.
This set of unmapped reads can be divided in four fractions: (i) reads matching to intergenic regions, (ii) reads matching to intronic regions, (iii) reads matching to the border of coding regions and UTRs, and (iv) non-mapped reads.
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When I read, I read.
I read and I read and I read.
I read you here.
"Chapter One," I read.
"I read," he said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com