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I had to see whether the genes I had previously discovered that controlled the division of the yeast cell were also relevant for human cells.
Thereby, we confirmed a pharmacokinetic mechanism which was previously discovered, i.e. that these two polymorphisms were associated with significantly decreased cytochrome P450 3A4 (CYP3A4) enzyme expression and activity [ 428].
The systematic structure activity relationships of previously discovered molecules (types I, II, III) were analyzed to design new molecules (type IV) by bioisosteric replacement of the amino group.
A series of new strobilurin pyrimidine analogs were designed and synthesized based on the structures of our previously discovered antiproliferative compounds I and II.
The new fossils are 220 million years older than any previously discovered.
How is the Neuschwanstein meteorite similar to a previously discovered meteorite?
Beta amyloid has long been implicated in Alzheimer's — and previously discovered mutations actually increased its production.
But in a Wednesday email, Rutgers referred to new information and "a review of previously discovered issues" as the reasons for Rice's termination.
Unlike some of the previously discovered e-mails, this one wasn't jocular, and it hadn't been written in haste.
Engineers have found a tiny crack in a fuel line of the space shuttle Columbia very similar to those previously discovered in two other shuttles, NASA said today.
The clincher is a reference to her brother, Charaxos – whose very existence has long been doubted, since he is mentioned nowhere in previously discovered fragments of Sappho.
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