Exact(1)
Given a causal network, the most basic question is: If I perturb gene X, what happens to gene Y?
Similar(58)
Even if a large cage effect E i perturbed a drug-treated mouse's phenotype, such that y i drug = x i T α drug + d i T β drug + E i + ε i, (10 then for matching mouse i′, y i ′ placebo = x i T α placebo + d i T β placebo + E i + ε i ′. (11 Subtracting Equation 10 from Equation 11 removes E i from the model.
In mouse, lack of Rab-GDI perturbed the functionality of different SV pools at the presynaptic site.
These relations were represented by a drug-pathway matrix, in which rows represent drugs, columns represent pathways, and the ijth element is 1, if drug i perturbs pathway j, and is 0 otherwise.
The basic idea is as follows: to reconstruct a regulatory network with n nodes, one first measures the state of the nodes in the wild-type and then performs at least n perturbation experiments: in experiment i node i is perturbed, whereas all other n − 1 nodes are screened whether they changed their state compared to the wild-type.
But I was perturbed, yes, I was".
When he watched the televised portion of the brawl, he said: "I was perturbed because I could foresee this happening.
To decide whether a perturbation of k induces a significant effect on node i (and is thus integrated as edge k → i in the perturbation graph) one can either use correlation analysis of the entire data or only direct variation measures quantifying the change of x i when perturbing x k.
Conversely, if IF i is high, gene i could aggregately perturb the pathway by a strong connection to others.
And yet, on December 3, 2014, the day the grand jury announced its landmark decision in the death of Eric Garner, the same day I was sworn into the New York Bar, I was perturbed and humbled by the brokenness of our justice system--as if I were seeing an aging parent as mortal for the first time.
Being a black woman and all--plus I'm a Haitian immigrant, which makes me a double insult--I was perturbed, to say the least.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com