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The primary target for CMVs will be modulation of antigen presentation in the endosomal system, either by retrieval of MHC I loaded with viral peptides into endosomal compartments or redirection of MHC I trafficking and disruption of endosomal peptide loading.
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Isn't it loaded with fat, sugar, dairy, additives, preservatives and caffeine?
The approach has since been extended to a general bimaterial interface geometry under mixed-mode I/II loading, with application to fatigue debonding of layered materials.
As I leave, loaded with pies, I thank the Lord I am not called Simon.
The characters here don't quite say, "I'm a sweet potato; I'm loaded with beta carotene," but the hokey pedantry is only slightly less obvious.
When I went back to ballet class, after many years (read "decades"), I was loaded with doubts.
The patients' PBMC were stained with HLA-I multimers loaded with the SVG9 and SLF9 epitopes and analyzed by multicolor flow cytometry.
I cannot ask the other to have ill-will towards me, when I am loaded with it myself.
"Hoping your kids do all right is a great instinct and I'm loaded with it," he said.
I'm loaded with Bank of America, Citigroup and JPMorgan Chase –good, we hope, for the next couple of years.
The TBC/collagen I composite loaded with the synthetic BMP-2-related peptide is a promising scaffold biomaterial for bone tissue engineering.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com